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Assays for Anticancer Drug Targets
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| Human DNA topoisomerase I |
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| Human DNA topoisomerase II |
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| Human PARP-1 |
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| Human DNA polymerase alpha |
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| Human DNA polymerase beta |
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Human DNA polymerase gamma
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| Human mitochondrial RNA polymerase |
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| Human kinases |
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| Human mitochondrial ClpP protease |
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Assays for Antibacterial Drug Targets
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| Bacterial DNA topoisomerase I |
(E. coli Topoisomerase I) |
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Bacterial DNA gyrases
Quinolone-resistant mutant E. coli gyrases
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(E. coli, S. aureus, P. aeruginosa gyrases)
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| Bacterial DNA topoisomerase IV |
(E. coli, S. aureus, S. pneumoniae, P. aeruginosa topo IV) |
| Bacterial DNA polymerases |
(E. coli, H influenzae, S. pneumoniae DNA Polymerase III) |
| Bacterial RNA polymerases |
(E. coli, S. aureus RNA polymerases, PNPase) |
| Bacterial DNA helicases |
(E. coli, H. influenzae, S. pneumoniae, P. aeruginosa DnaB) |
| Bacterial DNA primases |
(E. coli, H. influenzae, S. pneumoniae, S. aureus DnaG) |
| Bacterial DNA ligases |
(E. coli ligase) |
| Bacterial kinases |
(NAD Kinase, TMK, UMP Kinase, Guanylate kinase) |
| Bacterial beta lactamase |
(Bacterial beta lactamases) |
| Bacterial cell wall synthesis |
(MurA, MurC, MurD, MurE, MurF enzymes) |
| Bacterial Ddl |
(E. coli D-alanine—D-alanine ligase) |
| Bacterial GlmU |
(E. coli UDP-N-acetylglucosamine pyrophosphorylase) |
| Bacterial IspD |
(E. coli, P. aeruginosa methylerythritol phosphate cytidyltransferases) |
| Bacterial PncB |
(S. aureus, S. pneumoniae nicotinate phosphoribosyltransferases) |
| Bacterial biotin protein ligase |
(E. coli BirA) |
| M. Tuberculosis ClpP Protease |
(M. Tuberculosis ClpP1P2) |
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Assays for Antiviral and Bacteriophage Drug Targets
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| Bacteriophage T7 RNA polymerase |
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Assays for Proteases
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